The utility of bexarotene in mycosis fungoides and Sézary syndrome
نویسندگان
چکیده
منابع مشابه
The utility of bexarotene in mycosis fungoides and Sézary syndrome
Cutaneous T-cell lymphoma (CTCL) is an umbrella term that encompasses a group of neoplasms that have atypical T-lymphocytes in the skin. Mycosis fungoides (MF) is the most common type of CTCL and Sézary syndrome (SS) is the leukemic form. Treatment for CTCL is dependent on the stage of disease and response to previous therapy. Therapy is divided into skin-directed treatment, which tends to be f...
متن کاملMycosis fungoides and Sezary syndrome.
YCOSIS FUNGOIDES (MF) is an uncommon, indoM lent T-cell lymphoma first described by Alibert' in the early 1800s. It primarily involves the skin at early stages of the disease, with plaques being the typical feature. After a variable period of time, it may progress with development of cutaneous tumors and spread to visceral sites and lymph nodes (LNs).* SBzary syndrome (SS) is an erythrodermic v...
متن کاملMycosis fungoides and Sézary syndrome.
Mycosis fungoides and Sézary syndrome are the most common of the cutaneous T-cell lymphomas, which are a heterogeneous group of neoplasms that affect the skin as a primary site. Although the aetiologies of mycosis fungoides and Sézary syndrome are unknown, important insights have been gained in the immunological and genetic perturbations that are associated with these diseases. Unlike some B-ce...
متن کاملThe role of chemokines and chemokine receptors in mycosis fungoides
Background: Chemokines are a family of cytokines initially characterized by their capacity to induce chemotaxis, or directed leukocyte migrations. These receptors are activated by chemotactic cytokines called chemokines. Interactions between chemokines and chemokine receptors also are involved in tumorigenesis, migration and invasion of lymphoma cells.Methods: An English literature search...
متن کاملDiagnostics in mycosis fungoides and Sezary syndrome.
AIM The aim of this paper was to present diagnostic methods helping in the recognition of mycosis fungoides (MF) and Sezary syndrome (SS). BACKGROUND Mycosis fungoides is the most common form of primary cutaneous T-cell lymphomas. It is characterized by a distinctive long-term course and malignant T-cell proliferation. MF diagnosis is not easy, mainly due to the atypical clinical presentation...
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ژورنال
عنوان ژورنال: OncoTargets and Therapy
سال: 2015
ISSN: 1178-6930
DOI: 10.2147/ott.s61308